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Symptoms of a B12 deficiencywhich can develop slowly over time since your body can store B12may (or may not) include: Fatigue Weakness Headache Depression Pale skin Heart palpitations Loss of appetite Weight loss Pain, inflammation, and/or soreness in your mouth or tongue Erectile dysfunction Infertility Tingling in your hands and feet Trouble balancing Confusion or memory issues Health Benefits of B12 Injections The easiest way to up your vitamin B12 intake is to eat foods that are rich in the nutrient